Dimexide instructions for use

Dimethyl sulfoxide is a colorless liquid with an original sweetish odor, first synthesized by the chemist Zaitsev. Used in chemistry, medicine and cosmetology. The main active substance of the medicinal drug Dimexidum. The cost in pharmacy chains is from 36 to 229 rubles.

Used for acute inflammatory diseases of the locomotor system and skin pathologies. It has analgesic and antiphlogistic effects. Valued for its ability to pass through the cell membrane.

pharmachologic effect

External medicine for compresses and lotions. After application, the substance passes deeply through the tissue. It has a therapeutic effect and increases the permeability of beneficial substances of other medications.

Dimexide has:

  • fibrinolytic effect - promotes the dissolution of blood clots;
  • antiseptic - delays the development of microorganisms and disinfects;
  • anti-inflammatory - reduces fever;
  • anesthetic - blocks the transmission of impulses along nerve fibers, anesthetizes.

Accelerates the penetration of other medications through the skin without affecting the pharmacological properties of the latter. To achieve a quick therapeutic effect, compresses are used from a mixture of dimethyl sulfoxide and antimicrobial agents, heparin or thrombophlebitis.

The combination of dimexide with medicinal drugs enhances the effect of the latter. When combined with medications that have many side effects, the solution reduces the burden on the body.

For example, a combination of prednisolone and dimexide in a ratio of 80/20 made it possible to reduce the recommended dose of a hormonal drug without reducing the therapeutic effect. The use of a medicinal solution together with expensive drugs helps to save money and reduce the formation of side effects.

Release form

A colorless liquid of dimethyl sulfoxide comes in a glass bottle. Contained in antiphlogical and decongestant medications.

Essence packaged in glass bottles of 50 and 100 ml, packed in cardboard boxes. A colorless liquid with a light original aroma contains 100 ml - 100 g. dimethyl sulfoxide. Sold in pharmacies.

Gel packaged in tubes weighing 30 g. A colorless or slightly yellowish gel with an original odor contains 25 g of dimethyl sulfoxide per 100 grams.

Excipients:

  • nipagin - 0.05 g;
  • nipazole - 0.013 grams;
  • carmellose sodium - 2 g;
  • purified water.

Dimethyl sulfoxide is an active or excipient in ointments - Dolobene, Ketorol, Remisid, Capsicum. Designed for pain relief and inflammation treatment.

Indications for use

Dimexide is an antimicrobial, thrombolytic, antipyretic drug. Prescribed for problems with the musculoskeletal system:

  • rheumatoid arthritis;
  • sprains, bruises, burns;
  • subcutaneous tissue infiltrate;
  • inflammatory damage to the skin and subcutaneous vessels;
  • dermatitis, psoriasis, acne, furunculosis, mycoses, erysipelas, eczema, baldness;
  • ankylosing spondylitis;
  • thrombophlebitis;
  • localized scleroderma.

Prescribed for inflammatory processes of the skin with pain, redness, and decreased sensitivity. Used, in conjunction with other treatments, for tissue regeneration.

The main purpose of the drug is to transport the beneficial components of other medications through the skin and mucous membrane.

Contraindications

According to the instructions, Dimexide is prohibited for use when:

  • eye diseases such as glaucoma, cataracts;
  • heart diseases - angina pectoris, after a stroke;
  • abdominal problems - kidneys and liver;
  • hypersensitivity.

Side effects

After treatment, a garlicky smell appears from the mouth. Against this background, nausea and vomiting occur.

At the compress sites, local undesirable consequences are possible in the form of irritation, itching, burning.

Of the systemic undesirable effects that affect the functionality of the entire body, narrowing of the bronchi rarely develops.

Use during pregnancy


Tests have not been carried out on pregnant women, so dimethyl sulfoxide is prohibited during pregnancy and breastfeeding. According to reviews on websites, there are known cases of prescription for lactostasis. Lotions with dimexide are possible if breastfeeding is stopped.

Application for children

Medicines containing dimexide are prohibited for children under 12-16 years of age.

Netizens comment on the prescription of medication for infants. Probably, we are talking about diseases of pneumonia and bronchitis; pediatricians sometimes prescribe a weak concentrate of dimexide in a 1/19 ratio with water. Consultation with a doctor is required.

How to make a compress with dimexide

Dimethyl sulfoxide is diluted with clean water from the pharmacy. The ingredients are mixed in a bottle. A solution of 40-50% is used, but for sensitive areas 10-30%.

dimexide ml distilled water ml solution%
4 36 10
4 16 20
4 12 25
12 28 30
8 12 40
10 10 50
36 4 90

Dosage and Application

Dimeksid diluted with clean water is used for the skin in the form of applications. The folded fabric is moistened with the prepared solution and applied to the skin. The compress with dimexide is covered with plastic wrap and secured with a bandage. Leave the occlusive dressing on for 20 to 30 minutes. Application course from 10 to 15 days.

A 10% solution is used on highly sensitive areas of the skin for:

  • cleansing purulent-necrotic wounds;
  • treatment of sutures after surgery;
  • facial skin.
  • pathologies of the spine and joints;
  • treatment of the musculoskeletal system.

compress with dimexide

30% for the treatment of skin integrity disorders with:
burns:

  • purulent inflammation of soft tissues;
  • trophic ulcers.

40% for treating the tissue surface of the skin with:

  • inflammation of the skin - carbuncle and inflammation of the hair follicle - boil;
  • acne;
  • diseases caused by the bacterium streptococcus.

50% - with the autoimmune disease scleroderma.

How to treat

For the treatment of purulent pathologies, boils, trophic ulcers, 40% dimexide is used. Apply the product with sterile cotton wool or spray to problem skin three times a day.

For scleroderma, make a compress with 50% dimeksid. The fabric folded in several layers is dipped in the medicine, applied to the sore spot, and secured with a tight bandage. Keep for 15-20 minutes, do 3 times a day.

For the treatment of the musculoskeletal system with osteochondrosis, osteoarthritis, arthritis, a compress with a 20% solution is prescribed. The bandage is applied for 20 minutes once a day.

To treat the skin after surgery, use a 10% product. Make a compress with dimexide every 8 hours. The duration of treatment is determined by the doctor.

In case of skin damage or burns, apply 20% dimexide with cotton wool or a spray.

special instructions

Before applying the compress, it is recommended to test for allergies to the medication. Apply a small amount of product to your hand. If you feel itching or burning, wash off with plenty of water. In case of an allergic reaction, take antihistamines.

Elderly people are recommended to use the medication after consulting a doctor.

Drug interactions

The drug enhances the activity and toxicity of substances. It is recommended to use diluted, after consulting a doctor. As a result of studies, effects on other medications have been established.

Dimexide in combination with other medications:

  • increases the body's sensitivity to substances that cause surgical anesthesia;
  • activates the action of ethanol and insulin;
  • increases the effect of nitroglycerin, acetylsalicylic acid, butadione, quinidine on the body;
  • increases the sensitivity of microbes to antibiotics.

Increases the body's sensitivity to painkillers. For severe pain, use diluted dimexide with novocaine. The lotion is used once a day. An ampoule of 2% novocaine is poured onto a cloth soaked in 50% dimexide. Exposure time 20 minutes. If you feel a burning sensation and severe itching, remove the lotion and wash the skin with cold water.

Dimexide gel


Analgesic and anti-inflammatory transparent gel with a slight specific odor, for the treatment of radiculitis, arthritis, bruises. It has a pronounced thrombolytic and antiseptic effect. Used to treat acne, boils.

100 g of the drug contains 25 g of dimethyl sulfoxide. After the active substance penetrates the skin, the body becomes susceptible to other medications. It is allowed to use together with analgesic, antipyretic, anti-inflammatory drugs, heparin.

Dimexide ointment

Capsicum instructions

Some anti-inflammatory ointments contain dimethyl sulfoxide.

Remisid- antimicrobial, analgesic, antitumor agent containing the main active substance nimesulide. Dimethyl sulfoxide helps the beneficial substances of the drug easily penetrate to the area of ​​pain and inflammation.

Ketorol— the active substance of ketorolac tromethamine. Pain reliever, treats neuralgia, radiculitis, rheumatism. It does not cure the disease itself, but relieves pain and reduces the inflammatory process. Dimethyl sulfoxide helps the active substances quickly penetrate the skin and have a healing effect.

Capsicam— contains dimethyl sulfoxide among the active substances. Used for arthralgia, myalgia, and to warm up muscles before sports training.

Dolobene- contains three main components - dimexide, heparin, dexpanthenol. The German drug has proven itself to be the best. It has a rapid therapeutic effect for relieving pain during acute inflammatory processes and regenerating damaged tissues.

Dimexide for acne

Dimexide has proven itself to be a positive treatment for acne. Before the procedure, the body’s predisposition to contraindications is checked. A 50% solution is applied in a thin layer to the elbow and left for 10 minutes. If you feel a burning sensation or itching, stop taking the medicine.

Make lotions with a 30% solution. Moisten sterile cotton wool and lightly press it onto the areas of acne; if necessary, attach it to the sore spot with a band-aid. Remove the compress with dimexide after 15 minutes.
The duration of treatment is from 5 to 7 days.

For skin diseases, long-term compresses are prohibited.


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